Klotho

Product information

Alpha-Klotho is a transmembrane protein that declines with age and is one of the most extensively researched longevity-associated molecules in gerontology. Named after the Greek goddess who spun the thread of life, Klotho protein influences multiple aging pathways including insulin signaling, oxidative stress resistance, calcium homeostasis, and stem cell maintenance. Klotho deficiency accelerates aging phenotypes; Klotho supplementation extends lifespan and healthspan in multiple model organisms.

Our recombinant alpha-Klotho formulation delivers the bioactive extracellular domain of the protein, the form responsible for its systemic anti-aging effects. Research demonstrates Klotho's neuroprotective properties (supporting cognitive function and synaptic plasticity), renal protective effects (Klotho deficiency is implicated in chronic kidney disease), and regulation of vitamin D metabolism and phosphate homeostasis. This is longevity science at the protein level, direct supplementation of a master aging regulator that naturally declines with time.

Benefits

• Master longevity protein supplementation
• Cognitive function and neuroprotection
• Kidney health support
• Systemic aging pathway modulation
• Stem cell maintenance support
• Oxidative stress resistance

Specifications

Fill / pack

2x 10mcg vials

Format

Injectable

Serving

10mcg / dose

Servings per container

2 doses

Listed purity

99.7%

Molecular weight / composition

~130 kDa (extracellular domain)

Storage

Refrigerate 2-8°C